Cell-Extracellular Matrix Interactions in Cancer

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Articles

  1. Inhoudsopgave
  2. Extracellular matrix in gene expression profiling of cancer
  3. Alterations in Cell-Extracellular Matrix Interactions during Progression of Cancers
  4. STRUCTURE OF MAMMALIAN SKIN

The understanding of cancer has evolved rapidly over the last decade, particularly with discoveries regarding the role of physical factors, such as extracellular matrix ECM stiffness and cellular forces, in carcinogenesis.

Inhoudsopgave

Steven Adie, Biomedical Engineering, is developing a novel platform for volumetric time-lapse imaging of cellular forces and cell-induced changes in ECM mechanical properties during single and collective cancer cell migration. Current imaging methods to quantify ECM mechanical properties and local cellular forces only provide two-dimensional imaging. When they do support three-dimensional imaging, they do not provide long-range volumetric measurements of collective mechanical behavior with cellular resolution. Adie is developing quantitative reconstruction capabilities for volumetric imaging of cell traction forces and ECM mechanical properties.


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These new quantitative capabilities are being integrated with a fluorescence confocal microscopy module to demonstrate a novel imaging platform. This new platform has unprecedented capabilities for time-lapse imaging studies of biophysical cell-ECM interactions in three-dimensional environments. The novel three-dimensional imaging platform for systems mechanobiology research is helping lead to a deeper understanding of potential biophysical mechanical hallmarks of cancer.

Brekken and A.

Extracellular matrix in gene expression profiling of cancer

Sanderson, Y. Yang, A. Purushothaman, Y.

Khotskaya, J. Ritchie and V. Proteoglycans and Cancer A.

Alterations in Cell-Extracellular Matrix Interactions during Progression of Cancers

Tetraspanins in Cancer P. McDonaldand S. Golubovskaya, E. Beierle, S.


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Hochwald, E. Kurenova and W.

Focal Adhesion Kinase with the interacting proteins and signaling in cancer. Neem contact met mij op over Events Sprekers Incompany. Welkom terug. Uw account. Agenda Seminars Masterclasses e-learning Sprekers Incompany. Actueel Opinie Interviews Recensies Videos. Beoordeel zelf slecht matig voldoende goed zeer goed. Cell-Extracellular Matrix Interactions in Cancer.


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Gebonden, blz. Auteurs Over dit boek Artikelen en interviews Recensies. Samenvatting Rubriek: Geneeskunde.

STRUCTURE OF MAMMALIAN SKIN

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